ALTERNATIVES TO ANIMAL TESTING
Searchable databases and web resources
- Johns Hopkins Center for Alternatives to Animal Testing—CAAT
- https://norecopa.no/databases-guidelines/norina-database/ – Norina alternative database
- https://ntp.niehs.nih.gov/whatwestudy/niceatm/altbib – National Library of Medicine, Alternatives to Animals in Biomed
- PubMed
- The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) website
Antibody production alternatives
- Monoclonal Antibody Production: A Report of the Committee on Methods of Producing Monoclonal Antibodies, ILAR, National Research Council
- Antibody Resource Page
Additional alternative search links
- NAL Animal Use Alternatives Thesaurus: Produced by the US National Agricultural Library (NAL), this site provides a classification of terminology relating to alternatives and animal welfare, constituting a valuable resource in harmonizing the terms used in this field.
- ALTBIB (Bibliography on Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing): Produced by experts at the U.S. National Library of Medicine from MEDLARS searches, ALTBIB is an online bibliography of published alternatives presented as a searchable database and as individual issues that can be browsed.
- Animal Welfare Institute: This link provides access to the following databases:
- Environmental Enrichment for Primates: Annotated Database of Environmental Enrichment and Refinement of Husbandry for Nonhuman Primates
- Database of Refinement of Housing and Handling Conditions and Environmental Enrichment for Laboratory
- Animals: Rodents, Rabbits, Cats, Dogs, Ferrets, Farm Animals, Horses, Birds, Fishes, Amphibians and Reptiles and Refinement and Environmental Enrichment for All Laboratory Animals
- Viktor Reinhardt and Annie Reinhardt at the Animal Welfare Institute maintain these databases, which are searchable by keywords
- ICCVAM (The Interagency Coordinating Committee on the Validation of Alternative Methods)/ NICEATM (The National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods) https://ntp.niehs.nih.gov/whatwestudy/niceatm/iccvam https://ntp.niehs.nih.gov/whatwestudy/niceatm: ICCVAM unites representatives from 15 federal agencies that generate or use information from toxicological test methods to support human health or environmental risk assessments. ICCVAM is responsible for the coordination of the development and review of various alternative toxicological methods. NICEATM provides operational support to ICCVAM. The two groups advocate the harmonization of test methods nationally and internationally. This site provides links to the participating agencies and reports on their activities in reviewing alternative test methods.
- The Norwegian Reference Centre for Laboratory Animal Science & Alternatives (NORINA): The Laboratory Animal Unit, Norwegian School of Veterinary Science, Oslo, has compiled an English-language database of audiovisuals and other alternatives for use in the biological sciences. The primary purpose of the database is to offer an overview of possible alternatives or supplements to the use of animals in student teaching, at all levels from schools to universities. NORINA has a separate TextBase for textbooks addressing laboratory animal science.
- https://norecopa.no/alternatives/ Norecopa is Norway’s National Consensus Platform for the advancement of the 3Rs. Their web site has a wide range of relevant resources, but their 3R guide is particularly useful as it provides a searchable index of 3Rs resources. Produced in collaboration with the Animal Welfare Information Center at the US Department of Agriculture it is a database which provides an overview of guidelines, databases, journals, email lists, regulations and policies which may help researchers to implement the 3Rs when planning research that may involve animals.
- UK NC3Rs The NC3Rs is a UK-base scientific organization that works nationally and internationally with the research community to replace, refine and reduce the use of animals in research and testing